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Cardizem 30mg Tablet

Cardizem 30mg Tablet
-13 %
Product price4৳
Special price3৳
Stock Status
In Stock
Product code
8207
Brand

Product model Model
Total Reviews
Official Products 100% Official Products
Authorized Showroom Brand Bazaar
Cardizem 30mg Tablet
3৳
4৳
Ex Tax: 3৳

Cardizem 30mg Tablet-

Price in Bangladesh

 

Cardizem 30mg Tablet

Indications

Diltiazem is indicated in the prophylaxis and treatment of angina pectoris. It is used in the management of classical and vasospastic angina pectoris. It has also been used in the treatment of essential hypertension. It is used for prophylaxis of some selected supraventricular tachyarrhythmias.

Therapeutic Class

Calcium-channel blockers

Pharmacology

Diltiazem hydrochloride is a calcium channel antagonist. It is a peripheral and coronary vasodilator with some negative inotropic activity. Diltiazem inhibits cardiac conduction particularly at the sino-atrial and atrioventricular nodes. Diltiazem has the following actions: Antianginal: A direct dilatation of coronary arteries and arterioles proved oxygen supply to myocardial tissues. In addition dilatation of the peripheral vasculature reduces systemic pressure of cardiac "after load" which results in lessened stress and reduced oxygen requirements of the myocardial tissues. Antiarrhythmic: The inhibited influx of calcium ions in cardiac tissues result in slowed electrophysiological activity through the S-A and A-V nodes without affecting accessory bypass conduction or altering normal atrial action potential or intraventricular conduction. Antihypertensive: Reduces peripheral vascular resistance as a result of vasodilatation.

Dosage & Administration

Hypertension: Dosage needs to be adjusted by titration to individual patient needs. When used as monotherapy, usual starting doses are 120 to 240 mg once daily. Maximum antihypertensive effect is usually observed by 14 days of chronic therapy; therefore, dosage adjustments should be scheduled accordingly. The usual dosage range studied in clinical trials was 120 to 540 mg once daily. Current clinical experience with 540 mg dose is limited; however, the dose may be increased to 540 mg once daily. Angina: Dosages for the treatment of angina should be adjusted to each patient's needs, starting with a dose of 120 mg to 180 mg once daily. Individual patients may respond to higher doses of up to 540 mg once daily. When necessary, titration should be carried out over 7 to 14 days.

Interaction

Diltiazem Hydrochloride should be carefully administered in case of concomitant use with the following drugs.
  • Anti-hypertensive agents : effects of anti-hypertensive agents are enhanced
  • Propranolol : concentration of propranolol may be increased
  • Carbamazepine : plasma level of Carbamazepine may be increased and it may cause Carbamazepine induced toxic symptoms such as sleepiness, nausea, vomiting, vertigo etc.
  • Digoxin preparations : plasma level of Digoxin is increased
  • Cyclosporin : may increase serum cyclosporin concentration by 75% or more.

Contraindications

Diltiazem Hydrochloride is contraindicated in pregnant women or those of child bearing potential, patients with Sick Sinus syndromes, patients with second or third degree AV block, patients with severe bradycardia and patients who demonstrated hypersensitivity to the drug.

Side Effects

Diltiazem Hydrochloride produces few side effects and these are usually mild. Oedema, nausea, headache, finger swelling, skin rash, dizziness and asthenia have been reported. Other adverse effects include bradycardia, AV block, hypotension, gastrointestinal symptom, hyperactivity with associated psychiatric symptoms and mild elevation of liver function tests.

Pregnancy & Lactation

Pregnancy: There are no adequate and controlled studies to date with diltiazem in pregnant women, and the drug should be used during pregnancy only when the potential benefits justify the possible risk to the fetus. Lactation: Because diltiazem is distributed into milk, women receiving the drug should not breastfeed their infants; an alternative method of infant feeding should be used if diltiazem therapy is considered necessary in nursing women.

Precautions & Warnings

Patients with mild bradycardia or a prolonged PR interval should be observed closely. Diltiazem does not have a significant myocardial depressant effect and is well tolerated in patients with poor left ventricular function. The drug should be used with caution in patients with impaired hepatic or renal function.

Use in Special Populations

Elderly and patients with impaired hepatic or renal function: The recommended starting dose is 60 mg twice daily. The heart rate should be measured regularly in these groups of patients and the dose should not be increased if the heart rate falls below 50 beats per minute. Children: Not recommended.

Overdose Effects

Symptoms: Hypotension, bradycardia, heart block, heart failure, impaired conduction, ECG changes, arrhythmias, shock, altered mental status, cardiac arrest. Management: Symptomatic and supportive treatment. Gastric lavage and admin of activated charcoal may be initiated. Maintain appropriate ventilation. Charcoal hemoperfusion may be useful. Hypotension may be treated with fluids and vasopressor agents. Bradycardia, 2nd- or 3rd-degree AV block may be treated with IV atropine sulfate.

Reconstitution

Dilute with appropriate solution either dextrose 5% in water, normal saline, dextrose 5% in water with NaCl 0.45% to achieve desired vol of concentration.

Storage Conditions

Tablet/ capsule: Store at 25°C. Protect from light. Solution for injection: Store between 2-8°C. Do not freeze.

Brand Bazaar || Pharmacy Online Store in Bangladesh

অর্ডার করতে সরাসরি কল করুনঃ ☎ 01619550030 / 01799922318, অথবা আমাদের শো-রুমে চলে আসুন । ✅ 2০ টাকা, আপনাকে অগ্রিম প্রদান করে, অর্ডারটি কনফার্ম করতে হবে। অবশিষ্ট মূল্য কুরিয়ার অফিস থেকে পণ্য নেওয়ার সময়, কুরিয়ার আফিসে পেমেন্ট করতে হবে।

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Purchase & Delivery Process:

1.       Home Delivery inside Dhaka 50 TK, Outside of Dhaka Delivery Charge 150 TK. 2. After confirmation of the order, products will be delivered within 24 hours – 2 Days inside Dhaka and 48 hours – 5 days outside of Dhaka. 3. Outside of Dhaka, Customer have to pay 150Taka in advance 4. Outside of Dhaka delivery via courier service. 5. Product delivery duration may vary due to product availability in stock

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What is the Cardizem 30mg Tablet price in bd 2024?

The Model Prescription Medicine price in BD is 3৳. In today's market on 28-03-2024. Brand Bazaar offers you the lowest price of Model Prescription Medicine: 3৳ instead of 4৳ regular price. The Model Prescription Medicine is In Stock now in our store (Call us to know about details of this product). 6 customer buy this product From 1252 visitors. Follow us on Facebook to stay updated with the latest offers. Subscribe our YouTube channel for product reviews. You can Order Model online, pay with online payment gateway or Cash on delivery (in Dhaka city) and get 2-3 day Express delivery anywhere in Bangladesh or visit our Showroom for more gift.