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Fixocard 5mg+25mg Tablet

Fixocard 5mg+25mg Tablet
-13 %
Product price6৳
Special price5৳
Stock Status
In Stock
Product code
8305
Brand

Product model Model
Total Reviews
Official Products 100% Official Products
Authorized Showroom Brand Bazaar
Fixocard 5mg+25mg Tablet
5৳
6৳
Ex Tax: 5৳

Fixocard 5mg+25mg Tablet-

Price in Bangladesh

 

Fixocard 5mg+25mg Tablet

Indications

Amlodipine & Atenolol is indicated in:
  • Hypertension not controlled by monotherapy
  • Angina pectoris & hypertension co-existing diseases
  • Post MI patients
  • Refractory angina pectoris where nitrate therapy has failed

Therapeutic Class

Combined antihypertensive preparations

Pharmacology

Amlodipine is a dihydropyridine calcium antagonist that inhibits the transmembrane influx of calcium ions into vascular smooth muscle and cardiac muscle; it has a greater effect on vascular muscle than on cardiac muscle. Amlodipine is a peripheral vasodilator that acts directly on vascular smooth muscle to cause a reduction in peripheral vascular resistance and reduction in blood pressure. Amlodipine reduces tone, decreases coronary vasoreactivity and lowers cardiac demand by reducing afterload. Atenolol is a cardio selective beta blocker. The cardio selectivity is dose related. Atenolol causes a reduction in blood pressure by lowering cardiac output, decreasing the plasma renin activity and sympathetic outflow from CNS. Atenolol also causes a reduction in myocardial oxygen demand by virtue of its negative inotropic and negative chronotropic effects.

Dosage & Administration

The recommended dosage is one tablet daily of (Amlodipine 5 mg & Atenolol 50 mg) or (Amlodipine 5 mg & Atenolol 25 mg). Depending upon the therapeutic response, titration of the dosage is recommended. In elderly patients, it is advisable to initiate the therapy with ½ tablet of fixed dose combination of Amlodipine & Atenolol (i.e. 2.5 mg of Amlodipine & 25 mg Atenolol).

Interaction

Amlodipine has been safely administered with thiazide diuretics, beta blockers, alpha blockers, angiotensin converting enzyme inhibitors, long-acting nitrates, sublingual glyceryl trinitrate, non-steroidal anti-inflammatory agents, antibiotics, and oral hypoglycemic agents. In vitro data from studies with human plasma indicate that amlodipine has no effect on protein binding of the drugs tested (Digoxin, Phenytoin, Warfarin, or Indomethacin). Atenolol reduces the clearance of Disopyramide by 20%. Additive negative inotropic effects on the heart may be produced. At doses of 1 gm and above, Ampicillin may reduce Atenolol levels. Beta-blockers may decrease tissue sensitivity to Insulin and inhibit Insulin secretion, e.g. in response to oral antidiabetics. Atenolol has less potential for these actions.

Contraindications

Hypersensitivity to either component, sinus bradycardia, second and higher degrees of heart block, cardiogenic shock, hypotension, congestive heart failure, poor left ventricular function.

Side Effects

The combination of Amlodipine and Atenolol is well tolerated. Overall side effects include fatigue, headache, edema, nausea, drowsiness, anxiety and depression.

Pregnancy & Lactation

Atenolol crosses the placenta. So it is contraindicated in pregnancy. It should be avoided during lactation.

Precautions & Warnings

Atenolol may mask the symptoms of hyperthyroidism. It may also mask the symptoms of hypoglycaemia, as well as enhance the effects of hypoglycaemic agents in patients with diabetes mellitus.

Storage Conditions

Store in a cool dry place protected from light. Keep out of reach of children.

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What is the Fixocard 5mg+25mg Tablet price in bd 2024?

The Model Prescription Medicine price in BD is 5৳. In today's market on 29-03-2024. Brand Bazaar offers you the lowest price of Model Prescription Medicine: 5৳ instead of 6৳ regular price. The Model Prescription Medicine is In Stock now in our store (Call us to know about details of this product). 6 customer buy this product From 1310 visitors. Follow us on Facebook to stay updated with the latest offers. Subscribe our YouTube channel for product reviews. You can Order Model online, pay with online payment gateway or Cash on delivery (in Dhaka city) and get 2-3 day Express delivery anywhere in Bangladesh or visit our Showroom for more gift.